A team of leading South African environmental scientists from a range of institutions, has been formed under the auspices of the Department of Science and Innovation (DSI) to consider the environmental aspects of the epidemic in the country and region, including weather, climate and air pollution (COVID-19 Environmental Reference Group, CERG). This is just one aspect of DSI’s coordinated effort to mobilize South African scientific resources to help mitigate this national crisis. The team is advising the epidemiological modelling group of the National Department of Health on these issues.